
产品货号:
Z36978
中文名称:
IL-17/IL17A抗体
英文名称:
Anti-IL-17/IL17A Antibody (Clone#20B4.G10.F5)
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-IL-17/IL17A Antibody (Clone#20B4.G10.F5) |
指标别名 | CTLA 8;CTLA8;IL 17;IL 17A;IL17;IL-17;IL17A;IL-17A;interleukin 17A |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | ELISA,FCM,WB |
基因名称 | IL17A |
克隆号 | 20B4.G10.F5 |
抗体来源 | Rat |
免疫原 | This Mouse IL-17A monoclonal antibody was produced in rats by repeated immunizations with full length recombinant mouse IL-17A protein (produced in E.coli) followed by hybridoma development. |
计算分子量 | 18kDa |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
纯化方式 | This monoclonal antibody is purified by a multi-step process which includes delipidation,salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.This antibody is specific for mouse IL-17A protein.Cross-reactivity with IL-17A from other sources has not been determined. |
浓度 | 2.94mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store IL-17A antibody at -20℃ or below.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
背景资料 | Mouse Interleukin-17A (IL-17A),also known as CTLA-8,is a proinflammatory cytokine member of a six-species family of proteins (IL-17A-17F).Mouse IL-17A protein is a homodimer consisting of two 134 amino acids peptides.IL-17A is secreted mainly by activated CD4+ and CD8+ T lymphocytes and acts through its receptor,IL-17R,to induce the expression of many mediators of inflammation,most strikingly,those that are involved in the proliferation,maturation and chemotaxis of neutrophils.Elevated levels of IL-17A have been associated with several conditions,including rheumatoid arthritis,airway inflammation,allograft rejection,inflammatory bowel disease,psoriasis,cancer and multiple sclerosis.There is 58% identity between the amino acid sequence of human and mouse IL-17A.Anti-IL-17A antibody is ideal for investigators involved in Immunology research. |
Uniprot ID | Q62386 |
基因名全称 | Interleukin-17A |
推荐稀释比 | ELISA:1:10,000 Flow Cytometry:1:500 WB:1:1000 |
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